Impact Of imidacloprid On Nephrotic Function Of Wister Rats

Abstract

Pesticides are substances that meant to control pests includingall of the following :herbicide,insecticides which may include termiticide , neonicotinoide the most common of neonicotinoide is imidacloprid which is a systemique insecticide that acts as an insect neurotoxic. In this study we were interested to know his impact on nephrotic function of wistar rats by usine two defferent concentation 5 and 50 mg we used 12rats and devided them into 3 groups in each group we put 4 rats then we had treated the first group by concentration 5 mg and the second group with concentration50mg and we keep group as a control .our study is planned on many axes of experimentation :study of blood paramter bichemical paramters oxidative stress paramters . mitochondrial paramters .our result shown us at a concentration 50mg decrease in biochemical paramters , increase in blood paramters, increase in metochondrial paramters (swilling and permeability) decrease in GSH and MDAand GST level and increase in (CAT, GPX) levels and at a concentration 5 mg our result sown us no changed in all paramter compared to control group